赵雁雁

女，1983年生，副研究员，硕士生导师

电   话：025-86882241

E-mail：yyzhao@niglas.ac.cn

传   真：025-57714759

   赵雁雁，女，1983年生，安徽寿县人。2006年获华中农业大学水产养殖专业学士学位，2009年获华中农业大学水生生物学专业硕士学位，2012年获中国科学院水生生物研究所水生生物学专业博士学位，同年进入中国科学院南京地理与湖泊研究所工作，历任助理研究员，副研究员。主要从事蓝藻毒素生态环境毒性效应及毒性机制研究。 

   主持国家自然科学基金2项、中国科学院人才项目1项，江苏省自然科学基金2项，参与水专项、STS等国家及院级科研项目若干项。负责和参与的项目主要有：国家自然科学基金项目：“发育期微囊藻毒素-LR暴露致大鼠胰腺发育的损伤效应及其引发的糖尿病易感风险研究”；中国科学院青年创新促进会项目；江苏省优秀科学基金项目“水生态毒理学”；国家重点研发计划“水体污染控制与治理科技重大专项”；院重点部署项目“湖泊典型有机污染物的控制技术研发及示范”等。 

     目前以第一或通讯作者发表SCI学术论文10余篇，包括Environmental Science & Technology, Environment International, Journal of Hazardous Materials, Environmental Pollution，Chemosphere等生态环境领域主流期刊。 

(1)  Yanyan Zhao, Yunjun Yan, Liqiang Xie, Lixiao Wang, Yaojia He, Xiang Wan, Qingju Xue. Long-term environmental exposure to microcystins increases the risk of nonalcoholic fatty liver disease in humans: A combined fisher-based investigation and murine model study. Environment International, 2020, 138, 105648. 

(2)  Yanyan Zhao, Qing Cao, Yaojia He, Qingju Xue, Liqiang Xie, Yunjun Yan. Impairment of endoplasmic reticulum is involved in β-cell dysfunction induced by microcystin-LR. Environmental Pollution 2017, 223, 587-594. 

(3)  Yanyan Zhao, Qingju Xue, Xiaomei Su, Liqiang Xie, Yunjun Yan, Lixiao Wang, Alan D. Steinman. First identification of the toxicity of microcystins on pancreatic islet function in humans and the involved potential biomarkers. Environmental Science & Technology, 2016, 50, 3137-3144. 

(4)  Yanyan Zhao, Kun Shi, Xiaomei Su, Liqiang Xie, Yunjun Yan. Microcystin-LR induces dysfunction of insulin secretion in rat insulinoma (INS-1) cells: Implications for diabetes mellitus. Journal of Hazardous Materials, 2016, 314, 11-21. 

(5) Yanyan Zhao, Liqiang Xie, Yunjun Yan. Microcystin-LR impairs zebrafish reproduction by affecting oogenesis and endocrine system. Chemosphere, 2015, 120, 115-122. 

(6) Yanyan Zhao, Qingju Xue, Xiaomei Su, Liqiang Xie, Yunjun Yan, Alan D. Steinman. Microcystin-LR induced thyroid dysfunction and metabolic disorders in mice. Toxicology, 2015, 328, 135-141. 

(7) Yanyan Zhao, Ping Xie, Huihui Fan, Sujuan Zhao. Impairment of the mitochondrial oxidative phosphorylation system and oxidative stress in liver of crucian carp (Carassius auratus L) exposed to microcystins. Environmental Toxicology, 2014, 29, 30-39. 

(8) Yanyan Zhao, Ping Xie, Huihui Fan. Genomic profiling of microRNAs and proteomics reveals an early molecular alteration associated with tumorigenesis induced by MC-LR in mice, Environmental Science & Technology, 2012, 46, 34-41. 

(9) Yanyan Zhao, Qian Xiong, Ping Xie. Analysis of microRNA expression in embryonic development toxicity induced by MC-RR. PLoS One, 2011, 6, e22676. 

(10) Yanyan Zhao, Ping Xie, Xuezhen Zhang. Oxidative stress response after prolonged exposure of domestic rabbit to a lower dosage of extracted microcystins. Environmental Toxicology and Pharmacology, 2009, 27, 195-199. 

(11) Yanyan Zhao, Ping Xie, Rong Tang, Xuezhen Zhang, Li Li, Dapeng Li. In vivo studies on the toxic effects of microcystins on mitochondrial electron transport chain and ion regulation in liver and heart of rabbit. Comparative Biochemistry and Physiology Part C, 2008, 148, 204-210.